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Splien Latest news VideoWhat Is a Spleen and What Does it Do? - WebMD
There are other openings present for lymphatic vessels and nerves. Like the thymus , the spleen possesses only efferent lymphatic vessels. The spleen is part of the lymphatic system.
Both the short gastric arteries and the splenic artery supply it with blood. The germinal centers are supplied by arterioles called penicilliary radicles.
The spleen is innervated by the splenic plexus , which connects a branch of the celiac ganglia to the vagus nerve. The underlying central nervous processes coordinating the spleen's function seem to be embedded into the Hypothalamic-pituitary-adrenal-axis , and the brainstem , especially the subfornical organ.
The spleen is unique in respect to its development within the gut. While most of the gut organs are endodermally derived with the exception of the neural-crest derived adrenal gland , the spleen is derived from mesenchymal tissue.
However, it still shares the same blood supply—the celiac trunk —as the foregut organs. Enlargement of the spleen is known as splenomegaly.
It may be caused by sickle cell anemia , sarcoidosis , malaria , bacterial endocarditis , leukemia , pernicious anemia , Gaucher's disease , leishmaniasis , Hodgkin's disease , Banti's disease , hereditary spherocytosis , cysts , glandular fever mononucleosis or 'Mono' caused by the Epstein—Barr virus , and tumours.
Primary tumors of the spleen include hemangiomas and hemangiosarcomas. Marked splenomegaly may result in the spleen occupying a large portion of the left side of the abdomen.
The spleen is the largest collection of lymphoid tissue in the body. A spleen easily palpable below the costal margin in any child over the age of 3—4 years should be considered abnormal until proven otherwise.
Splenomegaly can result from antigenic stimulation e. The most common cause of acute splenomegaly in children is viral infection, which is transient and usually moderate.
Basic work-up for acute splenomegaly includes a complete blood count with differential, platelet count, and reticulocyte and atypical lymphocyte counts to exclude hemolytic anemia and leukemia.
Assessment of IgM antibodies to viral capsid antigen a rising titer is indicated to confirm Epstein—Barr virus or cytomegalovirus.
Other infections should be excluded if these tests are negative. Traumas , such as a road traffic collision , can cause rupture of the spleen , which is a situation requiring immediate medical attention.
Asplenia refers to a non-functioning spleen, which may be congenital , or caused by traumatic injury, surgical resection splenectomy or a disease such as sickle cell anaemia.
Hyposplenia refers to a partially functioning spleen. These conditions may cause  a modest increase in circulating white blood cells and platelets , a diminished response to some vaccines , and an increased susceptibility to infection.
Healthy blood cells can easily pass, but old or damaged red blood cells are broken down by large white blood cells. The spleen will save any useful components from the old blood cells, including iron, so they can be reused in new cells.
The spleen can increase in size in order to store blood. The organ can widen or narrow, depending on the body's needs.
At its largest, the spleen can hold up to a cup of reserve blood. According to Knowlton, spleen lacerations or ruptures "usually occur from trauma like a car accident or contact sports.
The Mayo Clinic reported that without emergency care, the internal bleeding could become life-threatening.
On the continuum of spleen breakage, a laceration refers to a lower-grade extent of injury, in which just a part of the spleen is damaged.
A ruptured spleen is the highest grade of broken spleen injury, according to HealthTap , an online network of doctors who answer health questions. Vaskovic J.
Radiology Key. Anomalies and anatomic variants of the spleen. Niknejad M, Hacking C. Polysplenia syndrome. Splenic implant assessment in trauma.
Chirurgia Bucur. The American Association for the Surgery of Trauma. Blunt splenic trauma. Updated May Your doctor will talk through these risks with you.
Living without a spleen If your spleen needs to be removed, other organs, such as the liver, can take over many of the spleen's functions.
Young children have a higher risk of serious infection than adults, but the risk is still small. This risk can be minimised by following simple precautions to prevent infection.
Vaccinations Check with your GP surgery that you have had all your routine childhood vaccinations. Signs of infection include: a high temperature a sore throat a cough a severe headache a headache with drowsiness or a rash abdominal pain redness and swelling around the surgical wound Your GP can prescribe a course of antibiotics for you to use if you get an infection.
If your infection becomes serious, you may be admitted to hospital. Beware of animal and tick bites Bites from animals and small blood-sucking parasites called ticks can cause infections.
Try to avoid tick bites by wearing clothes that cover your skin, particularly long trousers. If you become ill, get medical advice straight away.
Tell medical staff about your spleen problems Healthcare professionals will mark your health records to show that you do not have a working spleen. But always remember to tell any medical professionals that you see, including your dentist.
Germinal centres in the white pulp serve as the sites of lymphocyte production. Similar to the lymph nodes, the spleen reacts to microorganisms and other antigens that reach the bloodstream by releasing special phagocytic cells known as macrophages.
Splenic macrophages reside in both red and white pulp, and they serve to remove foreign material from the blood and to initiate an immune reaction that results in the production of antibodies.
The splenic cords in the red pulp in the spleen serve as important reservoirs for large quantities of macrophages and other phagocytic white blood cells called monocytes.
Studies have shown that upon severe tissue injury, such as that sustained during a heart attack , the spleen releases a legion of monocytes, which then travel through the bloodstream to the site of injury.
There they serve to regulate inflammation and to facilitate tissue healing. In animals who have had their spleens removed, the monocyte response is not observed at the site of tissue injury, and healing is less thorough.
In addition, humans who have had their spleens removed a procedure known as a splenectomy appear to be at increased risk of infections and, as they age, cardiovascular disease and possibly even certain types of cancer.
An enlarged spleen affects each of these vital functions. As your spleen grows larger, it filters normal red blood cells as well as abnormal ones, reducing the number of healthy cells in your bloodstream.
It also traps too many platelets. Excess red blood cells and platelets eventually can clog your spleen and affect normal functioning.
An enlarged spleen may even outgrow its own blood supply, which can damage or destroy sections of the organ.
Anyone can develop an enlarged spleen at any age, but certain groups are at higher risk, including:. Mayo Clinic does not endorse companies or products.
Advertising revenue supports our not-for-profit mission.Ein Spleen – auch Fimmel, Tick sowie eine Marotte oder Schrulle – bezeichnet umgangssprachlich meist abwertend eine leichte Verrücktheit oder fixe Idee. Der Begriff wird oft im Zusammenhang mit Exzentrikern verwendet. Begriffe von Hochdeutsch auf Platt und umgekehrt übersetzen, plattdeutsche Tonbeispiele, Schreibregeln und Suchfunktionen zu regelmäßigen und. was 'Splien' auf Plattdeutsch übersetzt bedeutet in Hochdeutsch, English, Nederlands. Alles auf Platt im niederdeutschen Wörterbuch. Ein Spleen (aus englisch spleen entlehnt; ausgesprochen [spliːn]) – auch Fimmel, Tick sowie eine Marotte oder Schrulle – bezeichnet umgangssprachlich. Your spleen is an organ located just below your left rib cage. Many conditions — including infections, liver disease and some cancers — can cause an enlarged spleen, also known as splenomegaly (spleh-no-MEG-uh-lee). An enlarged spleen usually doesn't cause symptoms. It's often discovered during a routine physical exam. The spleen is part of your lymphatic system, which fights infection and keeps your body fluids in balance. It contains white blood cells that fight germs. Your spleen also helps control the amount of blood in your body, and destroys old and damaged cells. Certain diseases might cause your spleen to swell. The spleen, in healthy adult humans, is approximately 7 centimetres ( in) to 14 centimetres ( in) in length. An easy way to remember the anatomy of the spleen is the 1×3×5×7×9×10×11 rule. The spleen is 1 by 3 by 5 inches (3 by 8 by 13 cm), weighs approximately 7 oz ( g), and lies between the 9th and 11th ribs on the left-hand sid. The spleen is a soft organ with a thin outer covering of tough connective tissue, called a capsule. There is a handy rule to remember the rough dimensions of the spleen, called the 1x3x5x7x9x The spleen is the largest organ in the lymphatic system. It is an important organ for keeping bodily fluids balanced, but it is possible to live without it. The spleen is located under the ribcage. Generally, it causes no health problems. Surgical recall. These veins are tributaries of the inferior mesenteric vein…. 1/23/ · The spleen also stores blood — the blood vessels of the spleen can expand significantly. In humans, around 1 cup of blood is kept in the spleen, ready to be released if there is a significant. Spleen problems and spleen removal Some people are born without a spleen or need to have it removed because of illness or injury. The spleen is a fist-sized organ in the upper left side of your abdomen, next to your stomach and behind your left ribs. 4/14/ · The spleen sits under your rib cage in the upper left part of your abdomen toward your back. It is an organ that is part of the lymph system and works as a drainage network that defends your body Author: Annie Stuart.